CRP(C-Reactive Protein)

CRP is a protein produced by the liver when inflammation or tissue damage occurs in the body. It is an acute-phase protein, meaning it increases rapidly when there is inflammation or infection.

Feature

■ Acute reaction substances produced in the body when there is inflammation

■ Acute phase response protein that appears in the bloodstream in response to inflammatory cytokines such as interleukin-6 (IL-6)

■ Biomarkers of systemic inflammatory response, non-specific indicators

■ hs-CRP is an indicator for assessing the risk of heart disease and estimating prognosis, and is the first test item recommended by the American Heart Association

Measurement Conditions

■ Test Procedure for Analyzers (Hitachi 7180)

- Assay Mode: 2 Point End 19-34

- Wave length(main/sub): 570/800nm

■ Open reagent

Performance

■ Linearity: 32 mg/dL

■ Sensitivity: Initial absorbance 0.4~0.8

■ Minimum detection limit (LOD): 0.007 mg/dL

■ Correlation: y= 1.03x – 0.03 (R2=0.999, n=81, Range=0.02~5.31 mg/dL)

■ Normal reference value: Serum 0.3 mg/dL or less (37℃)